Complex of hazard criteria for improvement of hygienic standards list of chemicals in water

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Abstract

Analysis of domestic (Russian) and foreign documents revealed the necessity to correct existing standards of chemicals in water according to the new data about previously unexplored toxicological properties including mutagenic, carcinogenic effects, effects on the endocrine system. It is advisable to correct safety levels within the structural sets based on the relationship “structure – biotransformation – activity”. It is necessary to review critically the MACs of aromatic compounds substantiated on the organoleptic sign of harmfulness. The standards of nine carcinogens are proposed to revise with considering the classification and safety levels. Determination of threshold concentration on general sanitary index of harmfulness may be excluded from the regulation system because self-purification processes not sufficient in the Russian climatic conditions are related to ecological indices. This hazard index creates a discrepancy between the assessment of the danger of drinking and surface waters. It is necessary to create unified MACs for groups of substances in view of the forms of their presence in water and matching of toxic mechanism of action in compliance with the principle “unity of standard and method of control”.

About the authors

R. A. Mamonov

Center for Strategic Planning and Management of Biomedical Health Risks

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

Z. I. Zholdakova

Center for Strategic Planning and Management of Biomedical Health Risks

Email: noemail@neicon.ru
Russian Federation

O. O. Sinitsyna

Center for Strategic Planning and Management of Biomedical Health Risks

Email: noemail@neicon.ru
Russian Federation

S. M. Yudin

Center for Strategic Planning and Management of Biomedical Health Risks

Email: noemail@neicon.ru
Russian Federation

Irina A. Pechnikova

Center for Strategic Planning and Management of Biomedical Health Risks

Email: labtox430@mail.ru

MD, PhD, senior researcher of the Laboratory of ecologо-hygienic assessment and prediction of the toxicity of substances , “Center for Strategic Planning and Management of Biomedical Health Risks,  Moscow, 119991, Russian Federation.

e-mail: labtox430@mail.ru

Russian Federation

References

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  12. Sinitsyna O.O., Zholdakova Z.I., Karamzin K.B., Tul’skaya E.A. Substantiation of generalized maximum allowable concentration of oxyethylidenediphosphonic acid and its derivatives in water. In: Proceedings of the 7th International Congress «Water: Ecology and Technology». Part II [Sbornik dokladov 7-go Mezhdunarodnogo kongressa «Voda: ekologiya i tekhnologiya». Chast’ II]. Moscow; 2006. (in Russian)
  13. Pechnikova I.A., Sinitsyna O.O., Zholdakova Z.I., Mamonov R.A. Comparative assessment of toxicity and danger sim-triazines in water for example derivatives of cyanuric acid and melamine. In: Proceedings of the VI Russian scientific-practical conference with international participation of young scientists and specialists «Environment and Health. Hygiene and Ecology of the urbanized territories», dedicated to the 85th anniversary of the State Organization «Institute of Human Ecology and Environmental Hygiene named after A.N. Sysin» of the Ministry of Health of Russia [Materialy VI Vserossiyskoy nauchno-prakticheskoy konferentsii s mezhdunarodnym uchastiem molodykh uchenykh i spetsialistov «Okruzhayushchaya sreda i zdorov’e. Gigiena i ekologiya urbanizirovannykh territoriy», posvyashchennaya 85-letiyu FGBU «NII ECh i GOS IM.A.N. Sysina» Minzdrava Rossii]. Moscow; 2016: 361–6. (in Russian)

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